Opportunity Information: Apply for RFA AG 21 025

This funding opportunity, RFA-AG-21-025, is a Small Business Innovation Research/Small Business Technology Transfer style grant mechanism using the NIH SBIR/STTR phased structure (R43/R44) and is run through the Department of Health and Human Services, National Institutes of Health, under CFDA 93.866. The core purpose is to stimulate small business-led research and development of practical tools, technologies, and training or education platforms that help people affected by Alzheimer's disease and related dementias manage the financial and legal realities that come with caregiving. The FOA is explicitly marked "Clinical Trial Not Allowed," which means applicants are expected to focus on product development, usability, feasibility, and related non-clinical-trial research activities rather than testing an intervention in a way that meets NIH's clinical trial definition.

The emphasis is on building cost-effective and customizable solutions aimed at caregivers, care partners, and families who must handle financial management and legal planning tasks that often become more complex as cognitive impairment progresses. In real-world terms, this can include guidance and structured support for budgeting and bill payment, managing accounts and benefits, tracking expenses related to care, identifying risks like fraud or financial exploitation, and navigating estate-related responsibilities. On the legal planning side, the FOA points to the kinds of planning activities that commonly arise in dementia care, such as preparing or understanding powers of attorney, advance directives, guardianship considerations, and other estate planning needs. The underlying problem being addressed is that these responsibilities can be confusing, time-sensitive, emotionally taxing, and expensive, especially for families who do not already have access to professional legal or financial services.

A central requirement is that proposed tools be accessible and appropriate for diverse populations across the socioeconomic spectrum. That signals that NIH is looking for products that do not only work for highly resourced families, but can also be used by people with limited income, limited time, varying levels of digital literacy, different languages, and different cultural expectations around family caregiving and financial decision-making. Competitive projects would typically show how the platform will reduce barriers to use (for example, low-cost delivery, mobile-friendly design, plain-language content, and support for multiple languages), and how customization will work so that materials can be tailored to different stages of disease, different family roles, and different legal and financial contexts.

Because this is an R43/R44 opportunity for small businesses, it is geared toward turning an idea into a deployable product through a phased R and D pathway. While the FOA summary does not list a dollar cap (the award ceiling is shown as 0), it does state an expected number of awards of six, suggesting a competitive program with a limited set of funded projects. The opportunity was created May 27, 2020, with an original closing date of November 12, 2020, so it is best understood as a specific past solicitation, but its content describes the kind of innovations NIH was seeking: scalable caregiver-facing education and decision-support platforms that make financial management and legal planning more understandable, more affordable, and easier to act on for families dealing with AD/ADRD.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Development of Cost-Effective and Customizable Training and Education Platforms for AD/ADRD Caregivers that Focus on Addressing Financial Management and Legal Planning (R43/R44 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
  • This funding opportunity was created on May 27, 2020.
  • Applicants must submit their applications by Nov 12, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Small businesses.
Apply for RFA AG 21 025

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