Opportunity Information: Apply for RFA RM 17 029

The grant opportunity titled "Innovative Adaptations to Simplify Existing Technologies for Manipulation and Analysis of Glycans (U01)" was a National Institutes of Health (NIH) funding call under the Department of Health and Human Services. It sat within the NIH Common Fund program area known as Accelerating Translation of Glycoscience Integration and Accessibility, which focuses on making glycoscience practical for a broader range of biomedical researchers. The basic idea behind the opportunity was to lower the technical, cost, and usability barriers that often keep non-specialist labs from studying glycans (complex carbohydrates) and glycosylation, even though these molecules play major roles in biological processes and disease.

The purpose of the program was not simply to invent entirely new platforms from scratch, but to create innovative adaptations that simplify existing technologies for glycan manipulation and analysis. In practice, that means taking methods that may already work in expert settings but are difficult to run, expensive to maintain, or hard to interpret, and re-engineering them into tools that are more accessible, more affordable, easier to adopt, and more straightforward to use correctly. The NIH framed this as a way to accelerate biomedical discovery by enabling many more researchers to include carbohydrate structure and function in their studies, rather than treating glycans as a specialized niche that requires dedicated glycoscience expertise.

This opportunity used the cooperative agreement mechanism (U01), which signals that NIH expected substantial programmatic involvement during the project period compared with a standard research grant. Cooperative agreements are commonly used when an agency wants to actively coordinate, guide, or integrate funded projects to achieve a broader program goal, such as tool development and dissemination. The funding instrument type was listed as a discretionary cooperative agreement, and the funding activity category was health, consistent with NIH's mission and the biomedical emphasis of the program.

In terms of eligibility, the announcement was broad and open to many organization types. Eligible applicants included various levels of government (state, county, city or township, special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, and multiple categories of nonprofit organizations, including both 501(c)(3) and non-501(c)(3) entities (excluding institutions of higher education in those nonprofit categories). It also allowed participation by Native American tribal governments (federally recognized), other tribal organizations, public housing authorities/Indian housing authorities, for-profit organizations (other than small businesses), and small businesses. The "Others" category indicated that additional clarifications could apply in the full announcement text, but the summary list already suggests a deliberate effort to include academic, nonprofit, governmental, and commercial developers who could build and distribute practical glycoscience tools.

The financial scope of the call was relatively modest and focused, with an award ceiling of $200,000 and an expected number of three awards. That combination typically points to targeted tool-adaptation projects with clear deliverables rather than large multi-center research programs. The timing indicates the opportunity was created on August 4, 2017, with an original closing date of October 27, 2017, meaning it was a time-limited solicitation aimed at moving quickly on a specific set of tool-development needs.

Overall, this funding opportunity was designed to help translate glycoscience into everyday biomedical research by supporting projects that make glycan-related technologies simpler, cheaper, and easier to implement. By doing so, NIH aimed to broaden participation beyond specialized glycoscience labs, enabling more researchers to investigate how carbohydrates contribute to health and disease through improved access to practical methods for glycan manipulation and analysis.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Innovative Adaptations to Simplify Existing Technologies for Manipulation and Analysis of Glycans (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
  • This funding opportunity was created on Aug 04, 2017.
  • Applicants must submit their applications by Oct 27, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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