Opportunity Information: Apply for W81XWH 19 LCRP CA

The DoD Lung Cancer Research Program (LCRP) Concept Award (FY19) is designed to fund bold, early-stage ideas in lung cancer research that could open up entirely new directions for the field. The emphasis is on exploring a highly innovative concept or an untested theory that tackles an important lung cancer problem, especially where the approach is genuinely different from what is already being done. This award is meant to help investigators chase promising, sometimes unexpected observations and take scientific risks that would be hard to support through more traditional mechanisms that expect a well-established foundation.

A key point of this opportunity is what it does not want to fund: incremental next steps of an ongoing, established research line. Instead, applicants need to make a clear case that the proposed work is conceptually novel and that it can meaningfully expand current knowledge or set up a new and inventive investigative path. The program recognizes that transformative research often starts without a large body of supporting evidence, so the Concept Award is structured to allow investigators to test an idea before it has accumulated extensive proof.

Because the goal is to enable high-risk, high-reward exploration, preliminary data is not expected and is not considered central to a strong application. While applicants are allowed to include preliminary results, proposals should stand on the strength of the idea itself, the logic behind it, and the potential for impact rather than relying on existing datasets to validate feasibility. In practice, the award is positioned as a springboard: the research supported here may produce the initial findings needed to compete for larger, follow-on grants later.

The opportunity also places strong emphasis on military health relevance. The LCRP is part of a broader mission to address the healthcare needs of military Service members, Veterans, and their families, and that relevance is factored into programmatic review. Applicants are encouraged to show a clear connection to the Military Health System, including lung cancer risks and needs that may be especially pertinent to these populations. One explicit example is attention to environmental or occupational exposures beyond tobacco, which can be particularly relevant in military contexts.

Several concrete pathways are highlighted for demonstrating military relevance. Proposals can incorporate military or Veteran populations, or use related biospecimens, data resources, databases, or existing programs. Collaboration is strongly encouraged, especially partnerships with investigators at DoD military treatment facilities or laboratories and with Department of Veterans Affairs medical centers and research labs. The program also notes the potential value of involving military consultants or specialty leaders connected to the Surgeons General in relevant clinical or research areas, which can strengthen alignment with real-world military health priorities.

Another theme is dual-use impact: applicants are encouraged to explain how the knowledge, tools, products, or technologies developed could be implemented in ways that meet military needs while also benefiting civilian patients. In other words, even when the science is broadly applicable, the proposal should spell out how it could translate into improvements for military and Veteran communities, whether through prevention, detection, biology, or care-related innovations.

Administratively, this funding opportunity is offered by the Department of Defense (Department of the Army, USAMRAA) under Funding Opportunity Number W81XWH-19-LCRP-CA. It is listed as a discretionary opportunity, using grant and/or cooperative agreement instruments, and falls under Science and Technology and other Research and Development (CFDA 12.420). Eligibility is described as unrestricted, meaning it is open to a wide range of applicant organizations, subject to any additional eligibility clarifications in the full announcement. The posting indicates an expected 14 awards, and while an award ceiling is not specified in the provided summary (listed as 0), applicants typically must rely on the full solicitation for budget limits, performance period details, and submission requirements. The opportunity was created May 1, 2019, with an original closing date of August 7, 2019.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Lung Cancer, Concept Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on May 01, 2019.
  • Applicants must submit their applications by Aug 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 14 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 19 LCRP CA

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FAQs: DoD Lung Cancer Research Program (LCRP) Concept Award (FY19)

What is the DoD LCRP Concept Award (FY19) meant to support?

It is designed to fund bold, early-stage lung cancer research ideas that could open entirely new directions for the field. The focus is on highly innovative concepts or untested theories that address an important lung cancer problem in a genuinely different way than current approaches.

How would you describe the type of research this award is looking for?

This award is aimed at high-risk, high-reward exploration. It is intended to help investigators pursue promising or unexpected observations and take scientific risks that are often difficult to fund through traditional mechanisms that expect a well-established foundation.

What kinds of proposals are specifically discouraged?

The opportunity explicitly discourages funding incremental next steps of an ongoing, established research line. Applicants need to show the work is conceptually novel rather than a routine extension of existing studies.

Is preliminary data required for a competitive application?

No. Preliminary data is not expected and is not considered central to a strong application. Proposals should be compelling based on the strength of the idea, the logic behind it, and its potential impact.

Can applicants include preliminary results if they have them?

Yes. Applicants are allowed to include preliminary results, but the proposal is expected to stand on the concept itself rather than relying on existing datasets to establish feasibility.

What is meant by "conceptually novel" in this context?

Conceptually novel means the proposed work introduces a new concept, approach, or untested theory that could meaningfully expand current knowledge or create a new investigative path in lung cancer research, rather than refining or slightly modifying what is already being done.

Why does the program emphasize risk-taking and early-stage ideas?

The program recognizes that transformative research often starts without a large body of supporting evidence. The Concept Award is structured to let investigators test a new idea before it has accumulated extensive proof.

What role does military health relevance play in this award?

Military health relevance is a major emphasis and is considered during programmatic review. Applicants are encouraged to clearly connect their proposed research to the healthcare needs of military Service members, Veterans, and their families, including risks and needs that may be especially pertinent to these populations.

What are examples of military-relevant lung cancer topics mentioned in the summary?

One explicit example is attention to environmental or occupational exposures beyond tobacco, which can be particularly relevant in military contexts.

How can an applicant demonstrate military relevance in their proposal?

The summary highlights several pathways, including incorporating military or Veteran populations, using related biospecimens, leveraging data resources or databases, or building on existing programs connected to military or Veteran health.

Are collaborations encouraged, and if so, with whom?

Yes. Collaboration is strongly encouraged, particularly partnerships with investigators at DoD military treatment facilities or laboratories and with Department of Veterans Affairs medical centers and research labs.

Does the opportunity mention involving military consultants or clinical leaders?

Yes. The summary notes that involving military consultants or specialty leaders connected to the Surgeons General in relevant clinical or research areas can strengthen alignment with real-world military health priorities.

What is meant by "dual-use impact" for this funding opportunity?

Applicants are encouraged to explain how the knowledge, tools, products, or technologies developed could be implemented to meet military needs while also benefiting civilian patients. Even if the science is broadly applicable, the proposal should spell out how it could translate into improvements for military and Veteran communities.

Is the award intended to lead to follow-on funding?

Yes. The Concept Award is positioned as a springboard. The research supported may generate initial findings that help investigators compete for larger, follow-on grants later.

Who is the sponsoring agency for this opportunity?

The opportunity is offered by the Department of Defense (Department of the Army, USAMRAA).

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number listed is W81XWH-19-LCRP-CA.

What type of funding instrument is used?

The summary indicates it uses grant and/or cooperative agreement instruments.

How is this opportunity categorized (CFDA number and program area)?

It falls under Science and Technology and other Research and Development with CFDA 12.420.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is open to a wide range of applicant organizations, subject to any additional eligibility clarifications in the full announcement.

How many awards are expected?

The posting indicates an expected total of 14 awards.

Is there an award ceiling listed in the provided summary?

No. In the provided summary, the award ceiling is not specified (listed as 0). Applicants typically need to consult the full solicitation for budget limits and related details.

Where should applicants look for budget limits, performance period details, and submission requirements?

The summary suggests relying on the full solicitation for budget limits, performance period details, and submission requirements, since those specifics are not included in the provided summary.

What were the posting and closing dates shown in the summary?

The opportunity was created on May 1, 2019, with an original closing date of August 7, 2019.

Is this listed as a discretionary opportunity?

Yes. It is listed as a discretionary opportunity in the provided summary.

What makes a strong application according to the summary?

A strong application clearly argues for conceptual novelty, explains the logic behind the idea, and makes a convincing case for potential impact. It also addresses military health relevance in a concrete way and avoids presenting the work as incremental continuation of an established research line.

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