Opportunity Information: Apply for TI 26 018
The Emergency Department Alternatives to Opioids Program (Funding Opportunity Number TI 26 018) is a discretionary grant opportunity from the Substance Abuse and Mental Health Services Administration (SAMHSA) designed to help hospitals and emergency departments strengthen safer pain care practices by reducing reliance on pharmacological opioid interventions. The main aim is to support the establishment and implementation of approaches that expand effective non-opioid and non-pharmacologic pain management options in hospital and emergency department settings, while also addressing the downstream harms that can follow opioid exposure in acute care. In practical terms, the program is intended to help participating organizations improve how pain is assessed and treated in the ED and related hospital environments so that patients receive appropriate relief while lowering the chance of opioid-related complications, future misuse, and potential overdose.
A central focus of this opportunity is preventing avoidable opioid initiation or escalation that can begin with treatment for acute pain. By investing in alternatives and updated clinical practices, the program seeks to reduce the harmful consequences sometimes associated with opioid use in emergency and hospital-based pain care. This includes promoting safer prescribing and care pathways that better match treatment intensity to patient need, and supporting broader clinical workflows that prioritize evidence-informed, patient-centered pain management without defaulting to opioids when other effective options exist.
Eligibility is limited by statute, meaning only certain applicant types can apply. Eligible applicants are hospitals and emergency departments, including freestanding emergency departments and rural emergency hospitals. This restriction signals that the funding is specifically meant to influence care at the point where many patients first receive pain treatment and where prescribing decisions can have long-term implications. The activity category is health, and the CFDA/Assistance Listing number associated with the program is 93.788.
From a funding standpoint, this is a grant (Funding Instrument Type: Grant) with an award ceiling of $500,000 per award. SAMHSA anticipates making approximately 12 awards under this opportunity. The opportunity was created on July 1, 2026, and the original application closing date is July 27, 2026. The program sits within SAMHSA's broader mission of reducing substance-related harms and improving behavioral health outcomes, and here it does so by supporting hospital and emergency department-led practice changes that can reduce unnecessary opioid exposure while maintaining high-quality pain care.Apply for TI 26 018
- The Substance Abuse and Mental Health Services Adminis in the health sector is offering a public funding opportunity titled "Emergency Department Alternatives to Opioids Program" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.788.
- This funding opportunity was created on 2026-07-01.
- Applicants must submit their applications by 2026-07-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 12 candidate(s).
- Eligible applicants include: Others.
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Emergency Department Alternatives to Opioids Program (TI 26 018) - FAQs
1) What is the Emergency Department Alternatives to Opioids Program?
The Emergency Department Alternatives to Opioids Program (Funding Opportunity Number TI 26 018) is a discretionary grant opportunity from the Substance Abuse and Mental Health Services Administration (SAMHSA). It is designed to help hospitals and emergency departments strengthen safer pain care practices by reducing reliance on pharmacological opioid interventions.
2) What is the main purpose of this grant opportunity?
The main aim is to support the establishment and implementation of approaches that expand effective non-opioid and non-pharmacologic pain management options in hospital and emergency department settings, while also addressing downstream harms that can follow opioid exposure in acute care.
3) What kinds of settings are intended to benefit from the program?
The program is focused on hospital and emergency department environments, including emergency departments and related hospital settings where acute pain is commonly assessed and treated and where initial pain treatment decisions can influence longer-term outcomes.
4) What problem is this program trying to address?
A central focus is preventing avoidable opioid initiation or escalation that can begin with treatment for acute pain. The program seeks to reduce harmful consequences sometimes associated with opioid use in emergency and hospital-based pain care, including opioid-related complications, future misuse, and potential overdose.
5) How does the program approach safer pain care?
Based on the information provided, the opportunity emphasizes updating clinical practices and investing in alternatives to opioids. It also promotes safer prescribing and care pathways that better match treatment intensity to patient need, along with clinical workflows that prioritize evidence-informed, patient-centered pain management without defaulting to opioids when other effective options exist.
6) Does the program require abandoning opioids entirely?
The information provided does not state that opioids must be eliminated. Instead, it emphasizes reducing reliance on pharmacological opioid interventions and avoiding unnecessary opioid exposure, while maintaining appropriate pain relief and high-quality pain care.
7) What types of pain management alternatives are emphasized?
The opportunity is intended to expand effective non-opioid and non-pharmacologic pain management options in hospital and emergency department settings. Specific modalities are not listed in the provided description, but the emphasis is on approaches that are not opioid-based and may include non-pharmacologic options.
8) Who is eligible to apply?
Eligibility is limited by statute. Eligible applicants are hospitals and emergency departments, including freestanding emergency departments and rural emergency hospitals.
9) Can freestanding emergency departments apply?
Yes. The eligible applicants specifically include freestanding emergency departments.
10) Are rural emergency hospitals eligible?
Yes. Rural emergency hospitals are explicitly included among eligible applicants.
11) Is eligibility open to organizations beyond hospitals and emergency departments?
No additional eligible applicant types are listed in the provided information. Eligibility is described as limited by statute to hospitals and emergency departments (including freestanding emergency departments and rural emergency hospitals).
12) What is the funding instrument type?
The funding instrument type is a grant.
13) What is the maximum award amount?
The award ceiling is $500,000 per award.
14) How many awards does SAMHSA expect to make?
SAMHSA anticipates making approximately 12 awards under this opportunity.
15) What is the program trying to improve in practical terms?
In practical terms, the program is intended to help participating organizations improve how pain is assessed and treated in the emergency department and related hospital environments so patients receive appropriate relief while lowering the chance of opioid-related complications and downstream harms.
16) What downstream harms are mentioned in relation to opioid exposure?
The description references downstream harms that can follow opioid exposure in acute care, including future misuse and potential overdose, as well as opioid-related complications.
17) When was this funding opportunity created?
The opportunity was created on July 1, 2026.
18) What is the application closing date?
The original application closing date is July 27, 2026.
19) What is the activity category for this opportunity?
The activity category is health.
20) What is the CFDA/Assistance Listing number?
The CFDA/Assistance Listing number associated with the program is 93.788.
21) Which federal agency is offering this opportunity?
The opportunity is offered by the Substance Abuse and Mental Health Services Administration (SAMHSA).
22) How does this opportunity align with SAMHSA's mission?
The program sits within SAMHSA's broader mission of reducing substance-related harms and improving behavioral health outcomes by supporting hospital and emergency department-led practice changes that can reduce unnecessary opioid exposure while maintaining high-quality pain care.
23) Why does the program focus on emergency departments and hospitals?
The provided description notes that the funding is specifically meant to influence care at the point where many patients first receive pain treatment and where prescribing decisions can have long-term implications.
24) What is the Funding Opportunity Number for this grant?
The Funding Opportunity Number is TI 26 018.
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