Opportunity Information: Apply for RFA DK 17 007
The Cystic Fibrosis Research and Translation Center (P30) funding opportunity (RFA-DK-17-007) is a National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) program designed to strengthen and accelerate cystic fibrosis (CF) research by supporting specialized “core center” infrastructure at institutions with an established record of excellence in CF science. Rather than funding a single research project, the P30 mechanism is meant to build shared capacity: it helps an institution organize people, services, and resources in a way that makes many individual CF research projects more effective, more collaborative, and more likely to translate discoveries into therapies.
At its core, this program supports both basic and clinical CF research by creating a hub that multiple investigators can rely on. The center model is intended to lower barriers that slow down research, such as lack of access to specialized technologies, standardized assays, biostatistical or informatics support, clinical research coordination, patient-oriented resources, or other highly technical capabilities that are expensive or inefficient to duplicate across separate labs. By concentrating these capabilities into shared cores, the program aims to improve rigor, reproducibility, efficiency, and cross-disciplinary collaboration, ultimately speeding progress toward developing and testing new treatments for CF.
The FOA specifies three major activity areas that the center must provide. First are Research Core services, meaning shared scientific cores that deliver specialized methods, technologies, and expertise to CF investigators. Second is a Pilot and Feasibility (P and F) program, which provides smaller, targeted internal awards to help investigators generate preliminary data, explore innovative ideas, or bring new researchers into CF, often serving as a bridge to larger independent NIH grants. Third is an Administrative Core that includes an enrichment program, which typically covers leadership, governance, evaluation and continuous improvement, coordination among cores, and community-building activities such as seminars, workshops, visiting speakers, trainee development, and other efforts that broaden participation and strengthen the CF research environment.
The opportunity is categorized as a discretionary grant and sits within the broader health-related funding activity area (CFDA 93.847). A wide range of applicant types are listed as eligible, including state and local governments, public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, for-profit organizations (other than small businesses), small businesses, and other applicants as allowed in the additional eligibility language. Even though eligibility is broad on paper, the nature of a P30 center competition generally implies that successful applicants will be organizations capable of demonstrating a strong, ongoing CF research base and the ability to run shared cores and a competitive pilot program.
From a funding standpoint, the announcement anticipated making about three awards, with an award ceiling of $750,000. The FOA was created on May 3, 2017, with an original closing date of July 20, 2017. NIDDK noted that it already supported seven CF Research and Translation Centers at the time, and it provided a link to information about those existing centers, signaling that this initiative fits into an established national network of CF center programs and is meant to sustain and expand that collaborative ecosystem.
Overall, this grant opportunity focuses on building and maintaining the infrastructure that enables high-impact CF research: shared cores that make advanced science and clinical translation more accessible, pilot funding that seeds innovation and new investigators, and administrative and enrichment activities that keep the center cohesive, collaborative, and productive. The intended outcome is a stronger, more connected CF research community capable of moving discoveries from basic mechanisms to clinical testing and, ultimately, to improved therapies for people living with cystic fibrosis.Apply for RFA DK 17 007
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Cystic Fibrosis Research and Translation Center (P30)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on May 03, 2017.
- Applicants must submit their applications by Jul 20, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the Cystic Fibrosis Research and Translation Center (P30) opportunity?
It is an NIH/NIDDK funding opportunity (RFA-DK-17-007) that supports a Cystic Fibrosis (CF) Research and Translation Center using the P30 “core center” mechanism. The goal is to strengthen and accelerate CF research by funding shared infrastructure that helps many CF research projects succeed, rather than funding a single stand-alone research project.
Which agency and institute sponsor this funding opportunity?
The program is sponsored by the National Institutes of Health (NIH), specifically the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What is the main purpose of a P30 “core center” grant in this program?
The P30 mechanism is intended to build shared capacity at an institution by organizing people, services, and resources into centralized “cores.” These shared cores are meant to make multiple CF research projects more effective, more collaborative, and more likely to translate discoveries into therapies.
Does this opportunity fund a single research project?
No. The emphasis is on building and maintaining center infrastructure (shared resources, services, and coordination) that supports many individual CF research projects across investigators.
What kinds of CF research does the center support?
The program is designed to support both basic and clinical CF research, with an overall emphasis on improving the ability to translate discoveries into therapies.
Why does the program emphasize shared cores and centralized resources?
Centralized cores are meant to lower common barriers to progress in CF research, such as limited access to specialized technologies, the cost and inefficiency of duplicating advanced capabilities in separate labs, and the need for standardized approaches that improve rigor, reproducibility, and efficiency.
What are the three major required activity areas described in the FOA?
The FOA specifies three major activity areas: (1) Research Core services (shared scientific cores), (2) a Pilot and Feasibility (P and F) program, and (3) an Administrative Core that includes an enrichment program.
What are Research Core services in the context of this center?
Research Core services are shared scientific cores that provide specialized methods, technologies, and expertise to CF investigators. These services are intended to make advanced capabilities broadly available across the CF research community at the institution.
What is a Pilot and Feasibility (P and F) program, and what is it for?
The P and F program provides smaller, targeted internal awards that help investigators generate preliminary data, explore innovative ideas, or bring new researchers into CF research. It often serves as a bridge to larger, independent NIH grants.
What is the Administrative Core expected to do?
The Administrative Core supports leadership, governance, evaluation and continuous improvement, and coordination among the various cores and center activities. It is designed to keep the center cohesive, efficient, and productive.
What is meant by the “enrichment program” within the Administrative Core?
The enrichment program typically includes community-building and capacity-building activities such as seminars, workshops, visiting speakers, trainee development, and other efforts that strengthen the CF research environment and broaden participation.
What types of barriers to CF research is this center model meant to reduce?
The center model is meant to reduce barriers such as lack of access to specialized technologies, lack of standardized assays, limited biostatistical or informatics support, challenges with clinical research coordination, and the high cost or inefficiency of duplicating highly technical capabilities across separate labs.
How does this opportunity aim to improve rigor and reproducibility?
By concentrating specialized technologies, standardized assays, and expert support into shared cores, the program is intended to promote consistent methods and higher-quality shared resources, which can improve rigor and reproducibility across multiple projects.
How does the center approach support translation to therapies?
The program is structured to improve collaboration and efficiency across basic and clinical research, and to provide resources that help move discoveries from mechanisms to clinical testing, increasing the likelihood that findings can translate into therapies for people living with CF.
What is the funding type and broader funding category for this opportunity?
The opportunity is categorized as a discretionary grant and is within the broader health-related funding activity area. It is listed under CFDA 93.847.
How many awards were anticipated under this announcement?
The announcement anticipated making about three awards.
What is the maximum award amount mentioned in the FOA?
The award ceiling listed in the announcement is $750,000.
When was the FOA created and when did it close?
The FOA was created on May 3, 2017, and had an original closing date of July 20, 2017.
Which organizations are listed as eligible applicants?
Eligible applicants listed include state and local governments; public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); tribal governments and tribal organizations; public housing authorities/Indian housing authorities; for-profit organizations (other than small businesses); small businesses; and other applicants as permitted by additional eligibility language.
If eligibility is broad, what kind of applicant does this program generally fit?
While eligibility is broad on paper, a P30 center competition generally implies that successful applicants will be organizations that can demonstrate a strong, ongoing CF research base and the ability to run shared cores and a competitive pilot program.
How does this FOA relate to existing CF centers supported by NIDDK?
NIDDK noted that it supported seven CF Research and Translation Centers at the time of the announcement and provided a link to information about those existing centers, indicating this opportunity fits into an established national network of CF center programs.
What is the intended overall outcome of funding a CF Research and Translation Center?
The intended outcome is a stronger, more connected CF research community with shared infrastructure, seeded innovation through pilot funding, and cohesive administration and enrichment activities, ultimately speeding progress from discovery to clinical testing and improved therapies for people with CF.
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| NIDDK Information Network Coordinating Unit: dkNET-CU (U24) Apply for RFA DK 17 010 Funding Number: RFA DK 17 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $635,000 |
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| Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24) Apply for RFA DK 17 034 Funding Number: RFA DK 17 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (DP1- Clinical Trial Not Allowed) Apply for RFA DK 17 011 Funding Number: RFA DK 17 011 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| NIDDK Partnerships with Professional Societies to Enhance Scientific Workforce Diversity and Promote Scientific Leadership (R25) Apply for RFA DK 17 015 Funding Number: RFA DK 17 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $135,000 |
| Diabetic Foot Consortium - Clinical Research Units (U01) Apply for RFA DK 17 014 Funding Number: RFA DK 17 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $275,000 |
| Lymphatics in Health and Disease in the Digestive System (R01 - Clinical Trials Not Allowed) Apply for RFA DK 17 016 Funding Number: RFA DK 17 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $499,999 |
| Multidisciplinary Urologic Research (KURe) Career Development Program (K12 Clinical Trial Optional) Apply for RFA DK 17 012 Funding Number: RFA DK 17 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| George M. O'Brien Urology Cooperative Research Centers Program (U54-Clinical Trial Optional) Apply for RFA DK 17 013 Funding Number: RFA DK 17 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
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| Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional) Apply for RFA DK 17 032 Funding Number: RFA DK 17 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| Elucidating the Effect of Glycemic Excursions on Patient Well-being and Cognitive Status in People with Type 1 Diabetes (T1D) (R01 Clinical Trial Optional) Apply for RFA DK 18 003 Funding Number: RFA DK 18 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Undergraduate Summer Research Education in Kidney, Urologic, and Hematologic Diseases (R25 Clinical Trial Not Allowed) Apply for RFA DK 18 006 Funding Number: RFA DK 18 006 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $125,000 |
| Human Islet Research Enhancement Center for the Human Islet Research Network (U24 Clinical Trial Not Allowed) Apply for RFA DK 18 012 Funding Number: RFA DK 18 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,200,000 |
| Ancillary Studies to the NIDDK Inflammatory Bowel Disease Genetics Consortium (R01- Clinical Trial Optional) Apply for RFA DK 18 017 Funding Number: RFA DK 18 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $200,000 |
| Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed) Apply for RFA DK 18 021 Funding Number: RFA DK 18 021 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Data Coordinating Center for the Diabetic Foot Consortium (U24 Clinical Trial Not Allowed) Apply for RFA DK 18 010 Funding Number: RFA DK 18 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| HEAL Initiative: Integrated Approach to Pain and Opioid Use in Hemodialysis Patients: The Hemodialysis Opioid Prescription Effort (HOPE) Consortium - Scientific and Data Research Center (U01 Clinical Trial Required) Apply for RFA DK 18 031 Funding Number: RFA DK 18 031 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Limited Competition for the Continuation of the Coordinating Center for Type 1 Diabetes TrialNet (U01 Clinical Trial Required) Apply for RFA DK 18 509 Funding Number: RFA DK 18 509 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $15,000,000 |
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